Impacts of Cigarette Smoking on the Tumor Immune Microenvironment in Esophageal Squamous Cell Carcinoma
Geng Wang, Chuqing Pan, Kexin Cao, Jingbing Zhang, Hui Geng, Kusheng Wu, Jing Wen, Caixia Liu
Abstract
Our findings indicated smoking may impair T cell-mediated immune response and supported the possible impacts of cigarette smoking in PD-L1 related research and therapy of ESCC.
Topics & Concepts
Stromal cellImmune systemMedicineImmunohistochemistryTumor microenvironmentEsophageal squamous cell carcinomaCytotoxic T cellInternal medicineOncologyCarcinomaCancer researchPathologyImmunologyBiologyIn vitroBiochemistryEsophageal Cancer Research and TreatmentCancer Immunotherapy and BiomarkersImmune cells in cancer