Preventing Retinal Detachment: Where are We? Implications from Stickler Syndrome
Robert A. Morris, Ferenc Kuhn, Timothy P. Sipos
Abstract
Abstract: Stickler syndrome, a rare inherited disease, carries a lifetime risk of rhegmatogenous retinal detachment (RRD) of up to 65%, higher than any other predisposing condition known. Both syndromic and non-syndromic eyes suffer RRD predominately from the same pathogenesis, vitreous tractional tears in the peripheral retina. Consequently, extraordinary publications in 2021– 2022, each reporting successful prevention of RRD in Stickler syndrome, using 360-degree (encircling) laser retinopexy, provide the first strong evidence upon which similar prophylaxis in non-syndromic eyes at high risk of RRD from peripheral retinal tears can confidently go forward. Keywords: retinal tear, retinal detachment, retinal detachment prevention, 360-degree laser retinopexy, stickler syndrome, encircling laser prophylaxis