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REM sleep behavior in Parkinson disease: Frequent, particularly with higher age

Heide Baumann‐Vogel, Hyun Hor, Rositsa Poryazova, Philipp O. Valko, Esther Werth, Christian R. Baumann

2020PLoS ONE33 citationsDOIOpen Access PDF

Abstract

This retrospective single-center polysomnography-based study was designed to assess the frequency of REM sleep behavior disorder (RBD) in consecutive patients with Parkinsonism, including Parkinson disease, dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration. We observed RBD in 77% of 540 Parkinson patients, with rising frequency at higher age and regardless of sex, in >89% of 89 patients with dementia with Lewy bodies or multiple system atrophy, and in <15% of 42 patients with progressive supranuclear palsy or corticobasal degeneration. Thus, the prevalence of RBD in sporadic Parkinson disease might be higher than previously assumed, particularly in elderly patients.

Topics & Concepts

Progressive supranuclear palsyCorticobasal degenerationDementia with Lewy bodiesParkinsonismREM sleep behavior disorderMedicineParkinson's diseasePolysomnographyDementiaAtrophyLewy bodySynucleinopathiesPediatricsDiseasePsychologyPathologyPsychiatryAlpha-synucleinElectroencephalographyParkinson's Disease Mechanisms and TreatmentsRestless Legs Syndrome ResearchSleep and Wakefulness Research
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