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A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the μ-Opioid Receptor

Renee A. Bouley, Zara Y. Weinberg, Helen V. Waldschmidt, Yu‐Chen Yen, Scott D. Larsen, Manojkumar A. Puthenveedu, J.J.G. Tesmer

2020Molecular Pharmacology25 citationsDOIOpen Access PDF

Topics & Concepts

InternalizationBeta adrenergic receptor kinaseG protein-coupled receptor kinaseG protein-coupled receptorKinomePharmacologyAgonistChemistryKinaseReceptorBiologyBiochemistryReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyProtein Kinase Regulation and GTPase Signaling
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