Antioxidant and copper-chelating power of new molecules suggested as multiple target agents against Alzheimer's disease. A theoretical comparative study
Maciej Spiegel, Tiziana Marino, Mario Prejanò, Nino Russo
Abstract
In this study, the scavenging activity against OOH radicals and the copper-chelating ability of two new synthesized molecules ( L1 and L2 ) that can act as multiple target agents against Alzheimer's disease have been investigated at the DFT level.
Topics & Concepts
ChelationChemistryAntioxidantCopperMoleculeRadicalScavengingReaction rate constantCombinatorial chemistryInorganic chemistryOrganic chemistryKineticsPhysicsQuantum mechanicsFree Radicals and AntioxidantsComputational Drug Discovery MethodsAntioxidant Activity and Oxidative Stress