Design and evaluation of in vivo bioavailability in beagle dogs of bilayer tablet consisting of immediate release nanosuspension and sustained release layers of rebamipide
Gang Jin, Hai V. Ngo, Jie Wang, Jing-Hao Cui, Qing‐Ri Cao, Chulhun Park, Minji Jung, Beom‐Jin Lee
Topics & Concepts
PoloxamerBioavailabilityBilayerDissolutionPoloxamer 407ChemistryChromatographyDosage formGranulationDissolution testingSolubilityStratum corneumNuclear chemistryMaterials sciencePharmacologyBiopharmaceutics Classification SystemMembranePolymerBiochemistryOrganic chemistryCopolymerMedicineComposite materialPathologyDrug Solubulity and Delivery SystemsAnalytical Methods in PharmaceuticalsAdvanced Drug Delivery Systems