<i>Bacillus amyloliquefaciens SC06</i> alleviates the obesity of ob/ob mice and improves their intestinal microbiota and bile acid metabolism
Zhonghua Zeng, Yuanhao Zhou, Yibin Xu, Song Wang, Baikui Wang, Zihan Zeng, Qi Wang, Xiaolin Ye, Lü Jin, Min Yue, Li Tang, Peng Zou, Pengwei Zhao, Weifen Li
Abstract
Bacillus amyloliquefaciens SC06 can ameliorate obesity in male ob/ob mice by reshaping the intestinal microbial composition, changing metabolites, with deep correlation between phenotypes, and regulating bile acid metabolism via the FXR signaling pathway.
Topics & Concepts
Bile acidGut floraBiologyBacteroidaceaeEndocrinologyBacteroidesInternal medicineBacillus amyloliquefaciensLipid metabolismLactobacillusPrevotellaMicrobiologyBiochemistryBacteriaMedicineGeneticsFermentationGut microbiota and healthDiet and metabolism studiesProbiotics and Fermented Foods