Replication stress impairs chromosome segregation and preimplantation development in human embryos
Katherine L. Palmerola, Selma Amrane, Alejandro De Los Angeles, Shuangyi Xu, Ning Wang, Joao de Pinho, Michael V. Zuccaro, Angelo Taglialatela, Dashiell J. Massey, Jenna Turocy, Alex Robles, Anisa Subbiah, Bob Prosser, Rogerio A. Løbo, Alberto Ciccia, Amnon Koren, Timour Baslan, Dieter Egli
Topics & Concepts
BiologyGeneticsDNA replicationMitosisChromosomeChromosome segregationAneuploidyControl of chromosome duplicationChromothripsisEmbryoCell biologyMolecular biologyGeneDNADNA damageGenome instabilityPrenatal Screening and DiagnosticsGenomics and Chromatin DynamicsDNA Repair Mechanisms