A thermo-sensitive and injectable hydrogel derived from a decellularized amniotic membrane to prevent intrauterine adhesion by accelerating endometrium regeneration
Xiaoyu Li, Peilin Li, Can Wang, Ting Shang, Haotian Han, Yongjuan Tong, Yubin Kang, Jianjun Fang, Lei Cui
Abstract
An injectable and thermo-sensitive hydrogel was derived from AM, which can be injected and solidified in vivo . The dAM-gel offers an option for preventing IUA by promotion of the re-epithelialization of the damaged endometrium.
Topics & Concepts
DecellularizationRegeneration (biology)AdhesionEndometriumAmnionChemistryMembraneCell biologyAmniotic fluidSelf-healing hydrogelsBiomedical engineeringAndrologyBiophysicsPregnancyBiologyObstetricsPolymer chemistryMedicineBiochemistryExtracellular matrixFetusGeneticsOrganic chemistryTissue Engineering and Regenerative MedicineElectrospun Nanofibers in Biomedical ApplicationsReproductive Biology and Fertility