Notch1 contributes to TNF-α-induced proliferation and migration of airway smooth muscle cells through regulation of the Hes1/PTEN axis
Xudong Li, Fan Zou, Yiyi Lu, Xinping Fan, Yuanyuan Wu, Xiaoli Feng, Xiuzhen Sun, Yun Liu
Topics & Concepts
HES1PTENNotch signaling pathwayCell growthDownregulation and upregulationTumor necrosis factor alphaCancer researchCell biologyBiologyChemistrySignal transductionImmunologyPI3K/AKT/mTOR pathwayGeneGeneticsBiochemistryDevelopmental Biology and Gene RegulationMast cells and histamineAsthma and respiratory diseases