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Targeting EGFR/PI3K/AKT/mTOR and Bax/Bcl-2/caspase3 pathways with ivermectin mediates its anticancer effects against urethane-induced non-small cell lung cancer in BALB/c mice

Marina N. Malak, El‐Shaimaa A. Arafa, Maha M. Abdel‐Fattah, Marwa M. Khalaf, Hany H. Arab, Mohamed A. Hamzawy

2025Tissue and Cell9 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayApoptosisProtein kinase BCancer researchChemistrymTORC2PharmacologyMedicineBiochemistrymTORC1Cancer, Stress, Anesthesia, and Immune ResponseChronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseases
Targeting EGFR/PI3K/AKT/mTOR and Bax/Bcl-2/caspase3 pathways with ivermectin mediates its anticancer effects against urethane-induced non-small cell lung cancer in BALB/c mice | Litcius