The preAR2 region (1458–1492) in factor V‐Short is crucial for the synergistic TFPIα‐cofactor activity with protein S and the assembly of a trimolecular factor Xa‐inhibitory complex comprising FV‐Short, protein S, and TFPIα
Björn Dahlbäck, Sinh Tran
Topics & Concepts
Tissue factor pathway inhibitorCofactorBiochemistryProtein SMolecular biologyBinding siteChemistryBiologyPlasma protein bindingProtein CTissue factorEnzymeCoagulationPsychologyPsychiatryBlood Coagulation and Thrombosis MechanismsS100 Proteins and AnnexinsBlood properties and coagulation