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HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway

Yiping Leng, Ruifang Chen, Runtai Chen, Si He, Xiaoli Shi, Xiaoyu Zhou, Zhen Zhang, Alex F. Chen

2020Biochemical and Biophysical Research Communications35 citationsDOI

Topics & Concepts

PyroptosisHMGB1Caspase 1CathepsinCell biologyChemistryInflammationCathepsin BProgrammed cell deathCathepsin SGene silencingEndothelial stem cellApoptosisBiologyImmunologyBiochemistryEnzymeGeneIn vitroInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideNeutrophil, Myeloperoxidase and Oxidative Mechanisms
HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway | Litcius