JAK–STAT Targeting Offers Novel Therapeutic Opportunities in Sepsis
Raphaël Clère-Jehl, Alexandre Mariotte, Ferhat Meziani, Seiamak Bahram, Philippe Georgel, Julie Helms
Topics & Concepts
SepsisSystemic inflammatory response syndromeJanus kinaseImmunosuppressionstatSeptic shockJAK-STAT signaling pathwayImmunologyMedicineSignal transductionSTAT proteinMyelopoiesisBiologyCytokineHaematopoiesisTyrosine kinaseCell biologySTAT3Stem cellCytokine Signaling Pathways and InteractionsPharmacological Effects of Natural CompoundsImmune Response and Inflammation