PPh<sub>3</sub>-Triggered Tandem Synthesis of 2,3-Disubstituted Benzofuran Derivatives from <i>o</i>-Quinone Methides with Acyl Chlorides
Yuhong Ma, Xiaoyu He, Long Wang, Qing‐Qing Yang
Abstract
A PPh3-triggered tandem strategy for the efficient synthesis of valuable 2,3-disubstituted benzofuran derivatives in generally good to high yields from aryl or alkyl acyl chlorides and o-quinone methides has been developed. This method features mild reaction conditions, simple operation, and a broad substrate scope.
Topics & Concepts
ChemistryBenzofuranTandemQuinoneAlkylArylSubstrate (aquarium)Combinatorial chemistryReaction conditionsOrganic chemistryCatalysisMaterials scienceGeologyComposite materialOceanographySynthesis of Indole DerivativesSulfur-Based Synthesis TechniquesChemical Synthesis and Reactions