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COVID-19 and vaping: risk for increased susceptibility to SARS-CoV-2 infection?

Kielan Darcy McAlinden, Mathew Suji Eapen, Wenying Lu, Collin Chia, Greg Haug, Sukhwinder Singh Sohal

2020European Respiratory Journal64 citationsDOIOpen Access PDF

Abstract

With great interest we read and commend the study done by Russo et al. [1], highlighting their findings that nicotine induces an increase in angiotensin-converting enzyme 2 (ACE-2) expression in human bronchial epithelial cells (HBEpC) and is mediated by α7-subtype nicotinic receptors (α7-nAChR). It raises the concern that all electronic nicotine-delivery systems may put users at greater risk of succumbing to coronavirus disease 2019 (COVID-19). Absolute cessation of any tobacco product in any form: implications for COVID-19 <https://bit.ly/3cyk9ra> Clifford Craig Foundation Launceston General Hospital, Rebecca L. Cooper Medical Research Foundation.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)NicotineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Angiotensin-converting enzyme 2Virology2019-20 coronavirus outbreakBetacoronavirusDiseaseCoronavirusImmunologyInfectious disease (medical specialty)Internal medicineOutbreakSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCOVID-19 and Mental Health
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