Electrochemical Aerobic Oxidative Cleavage of (sp<sup>3</sup>)C–C(sp<sup>3</sup>)/H Bonds in Alkylarenes
Tong Shen, Shuai Liu, Jianyou Zhao, Nengyong Wang, Le Yang, Jintao Wu, Xu Shen, Zhong‐Quan Liu
Abstract
An electrochemistry-promoted oxidative cleavage of (sp3)C–C(sp3)/H bonds in alkylarenes was developed. Various aryl alkanes can be smoothly converted into ketones/aldehydes under aerobic conditions using a user-friendly undivided cell setup. The features of air as oxidant, scalability, and mild conditions make them attractive in synthetic organic chemistry.
Topics & Concepts
ElectrochemistryOxidative cleavageChemistryCleavage (geology)Oxidative phosphorylationArylElectrochemical cellBond cleavageMedicinal chemistryCombinatorial chemistryOrganic chemistryCatalysisElectrodeMaterials sciencePhysical chemistryBiochemistryFracture (geology)AlkylComposite materialRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions