Challenges in treatment of patients with acute leukemia and COVID-19: a series of 12 patients
Susanne Ghandili, Susanne Pfefferle, Kevin Roedl, Piet Sonnemann, Panagiotis Karagiannis, Olaf Boenisch, Stefan Kluge, Stefan Schmiedel, Harald Ittrich, Holger Rohde, Marc Lütgehetmann, Katja Weisel, Carsten Bokemeyer, Dominic Wichmann, Walter Fiedler, Dominik Jarczak, Franziska Modemann
Abstract
Key Points Patients with acute leukemia present with a prolonged and severe course of COVID-19, which is paralleled by high rates of viremia. Low-intensive chemotherapy seems to be more feasible in patients with acute myeloid leukemia and concomitant SARS-CoV-2 infection.
Topics & Concepts
Myeloid leukemiaMedicineConcomitantViremiaCoronavirus disease 2019 (COVID-19)LeukemiaAcute leukemiaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Chemotherapy2019-20 coronavirus outbreakCytarabineImmunologyInternal medicineOncologyVirologyVirusOutbreakDiseaseInfectious disease (medical specialty)Neutropenia and Cancer InfectionsAcute Myeloid Leukemia ResearchHematological disorders and diagnostics