Sorafenib combined with STAT3 knockdown triggers ER stress-induced HCC apoptosis and cGAS-STING-mediated anti-tumor immunity
Xueyao Wang, Rui Hu, Zhenwei Song, Huajun Zhao, Zhaoyi Pan, Yujie Feng, Yating Yu, Qiuju Han, Jian Zhang
Topics & Concepts
SorafenibGene knockdownCancer researchApoptosisHepatocellular carcinomaTumor microenvironmentImmune systemMedicineSTAT3ImmunologyBiologyBiochemistryinterferon and immune responsesImmune Cell Function and InteractionCytokine Signaling Pathways and Interactions