A green approach for the synthesis of 2-substituted benzoxazoles and benzothiazoles via coupling/cyclization reactions
Hai Truong Nguyen, Trinh Hao Nguyen, Dung Duc Pham, Cong Tien Nguyen, Phuong Hoang Tran
Abstract
nanoparticles (LAIL@MNP) under solvent-free sonication. The reaction was performed under mild conditions and only produced water as a sole byproduct. The reactions under solvent-free sonication showed advantages of faster reaction rate (30 min) and high yields of the products (up to 90%). Moreover, the LAIL@MNP material was easily separated from the reaction mixture and can be recycled for five consecutive runs with a slight decrease in its catalytic performance (from 82 to 73%).
Topics & Concepts
Coupling (piping)Combinatorial chemistryChemistryComputer scienceEngineeringMechanical engineeringMulticomponent Synthesis of HeterocyclesChemical Synthesis and ReactionsSulfur-Based Synthesis Techniques