Rational design, synthesis, biological evaluation and molecular docking studies of chromone-pyrimidine derivatives as potent anti-cancer agents
Abhijit Kantankar, Y. Jayaprakash Rao, G. Mallikarjun, Y. Hemasri, Raghava Reddy Kethiri
Topics & Concepts
ChromoneHeLaChemistryK562 cellsPyrimidineCell cultureCancer cellDocking (animal)Chronic myelogenous leukemiaIn vitroLeukemiaStereochemistryBiochemistryCancerCancer researchImmunologyBiologyMedicineNursingGeneticsSynthesis of Organic CompoundsMulticomponent Synthesis of HeterocyclesSynthesis and biological activity