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USP14-IMP2-CXCL2 axis in tumor-associated macrophages facilitates resistance to anti-PD-1 therapy in gastric cancer by recruiting myeloid-derived suppressor cells

Li You, Qian Wang, Tianxue Zhang, Hong‐Wei Xiao, Mengjiao Lv, Hong Lv, Li Deng, Xuyao Zhang, Yu Zhang

2025Oncogene16 citationsDOI

Topics & Concepts

BiologySuppressorCancer researchCancerTumor microenvironmentMyeloid-derived Suppressor CellTumor cellsImmunologyGeneticsRNA modifications and cancerImmune cells in cancerImmune Cell Function and Interaction
USP14-IMP2-CXCL2 axis in tumor-associated macrophages facilitates resistance to anti-PD-1 therapy in gastric cancer by recruiting myeloid-derived suppressor cells | Litcius