Litcius/Paper detail

Canagliflozin shares common mTOR and MAPK signaling mechanisms with other lifespan extension treatments

Eric P. Jiang, Arjun Dinesh, Sohan Jadhav, Richard A. Miller, Gonzalo G. Garcia

2023Life Sciences23 citationsDOIOpen Access PDF

Topics & Concepts

mTORC1MAPK/ERK pathwayEIF4EPI3K/AKT/mTOR pathwaySignal transductionBiologyPhosphorylationTranslation (biology)EndocrinologyPharmacologyCell biologyInternal medicineMedicineMessenger RNAGeneticsGeneGenetics, Aging, and Longevity in Model OrganismsFOXO transcription factor regulationGenomics, phytochemicals, and oxidative stress