PFO5DoDA disrupts hepatic homeostasis primarily through glucocorticoid signaling inhibition
Chang Wang, Huayu Fu, H. J. Yang, Lei Liu, Fenghong Zhang, Chunyu Yang, Hongyuan Li, Jiamiao Chen, Qi Li, Xiaolin Wang, Yaorui Ye, Nan Sheng, Yong Guo, Jiayin Dai, Guowang Xu, Xinyu Liu, Jianshe Wang
Topics & Concepts
TransactivationPerfluorooctanoic acidGlucocorticoid receptorPeroxisome proliferator-activated receptorReceptorChemistryPeroxisomeAgonistNuclear receptorBioaccumulationHuman healthBiochemistryPharmacologyBiologyGene expressionTranscription factorGeneEnvironmental chemistryMedicineEnvironmental healthPer- and polyfluoroalkyl substances researchToxic Organic Pollutants ImpactVitamin D Research Studies