Mechanotransduction of stem cells for tendon repair
Haonan Wang, Yong‐Can Huang, Guoxin Ni
Abstract
several signaling pathways. In order to better understand the stem-cell response to mechanical stimulation and the potential mechanism of the tendon repair process, in this review, we summarize the source and role of endogenous and exogenous stem cells active in tendon repair, describe the mechanical response of stem cells, and finally, highlight the mechanotransduction process and underlying signaling pathways.
Topics & Concepts
MechanotransductionMechanosensitive channelsCell biologyTendonStem cellMechanobiologyPhysical StimulationAnatomyMedicineStimulationBiologyNeuroscienceInternal medicineIon channelReceptorTendon Structure and TreatmentCellular Mechanics and InteractionsExercise and Physiological Responses