Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma
Luning Qin, Heng Zhang, Qingqing Li, Ting Wu, Shan-bin Cheng, Kaiwen Wang, Yue Shi, Hao-ran Ren, Xue-wu Xing, Cheng Yang, Tong Sun
Abstract
Collectively, we identified VDBP as an important prognostic biomarker in HCC patients and uncovered it as a therapeutic target for enhancing the efficacy of immune therapy.
Topics & Concepts
Vitamin D-binding proteinVasculogenic mimicryCalcitriol receptorHepatocellular carcinomaCancer researchBiologyVitamin D and neurologyChemistryMedicineInternal medicineCancerEndocrinologyMetastasisVitamin D Research StudiesCancer Immunotherapy and BiomarkersCancer, Hypoxia, and Metabolism