IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer
Wenjuan Gao, Huiping Wen, Luyu Liang, Xiaoli Dong, Renle Du, Wei Zhou, Xuehui Zhang, Chunze Zhang, Rong Xiang, Na Li
Abstract
population with STAT3 signaling inhibition combined with anti-PD-L1 antibody can increase the therapeutic efficacy of chemotherapeutic agents for breast cancer. This study thus introduces a promising novel strategy for breast cancer therapy.
Topics & Concepts
Tumor microenvironmentCancer researchCancerBreast cancerMedicineChemistryInternal medicineTumor cellsCancer Cells and MetastasisCancer Research and TreatmentsImmunotherapy and Immune Responses