Overcoming C797S mutation: The challenges and prospects of the fourth-generation EGFR-TKIs
Hongyi Zhao, Xiao-Xiao Xi, Minhang Xin, San‐Qi Zhang
Topics & Concepts
Epidermal growth factor receptorOsimertinibCancer researchErlotinibTyrosine kinaseLung cancerProtein kinase domainMutantChemistryCancerMedicineBiologyOncologyReceptorInternal medicineGeneticsGeneLung Cancer Treatments and MutationsQuinazolinone synthesis and applicationsCancer therapeutics and mechanisms