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Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils

Qin Cao, David R. Boyer, M.R. Sawaya, P. Ge, David Eisenberg

2020Nature Structural & Molecular Biology148 citationsDOIOpen Access PDF

Topics & Concepts

AmylinFibrilAmyloid (mycology)Amyloid fibrilChemistryBiophysicsPeptideProtein structureIsletBiochemistryAmyloid βBiologyInsulinPathologyEndocrinologyMedicineDiseaseInorganic chemistryAlzheimer's disease research and treatmentsProtein Structure and DynamicsEnzyme Structure and Function
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