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Zero-Contrast Left Atrial Appendage Closure in Patients With Chronic Kidney Disease

Tadatomo Fukushima, Masato Fukunaga, Akihiro Isotani, Miho Nakamura, Ko Yamamoto, Kenichi Ishizu, Takashi Morinaga, Shinichi Shirai, Kenji Andò

2023Circulation Journal11 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Left atrial appendage closure (LAAC) usually requires contrast medium during the procedure. However, patients with chronic kidney disease (CKD) are at high risk of developing contrast nephropathy. This study aimed to assess the safety and feasibility of zero-contrast LAAC in patients with CKD. METHODS AND RESULTS: Zero-contrast LAAC was attempted in 15 patients with CKD Stages 3b-5 who were not on hemodialysis. All procedures were performed successfully, without any periprocedural complications. At the 45-day follow-up, no device-related complications or acute kidney disease were observed. CONCLUSIONS: The strategy of zero-contrast LAAC in patients with CKD can be an acceptable option.

Topics & Concepts

MedicineKidney diseaseHemodialysisCardiologyInternal medicineContrast (vision)Closure (psychology)AppendageContrast-induced nephropathyNephropathyRadiologySurgeryDiabetes mellitusEconomicsComputer scienceEndocrinologyMyocardial infarctionArtificial intelligencePercutaneous coronary interventionAnatomyMarket economyAtrial Fibrillation Management and OutcomesAcute Kidney Injury ResearchPericarditis and Cardiac Tamponade
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