Soluplus®-based dissolving microarray patches loaded with colchicine: towards a minimally invasive treatment and management of gout
Qonita Kurnia Anjani, Akmal Hidayat Bin Sabri, Natalia Moreno‐Castellanos, Emilia Utomo, Álvaro Cárcamo-Martínez, Juan Domínguez‐Robles, Luki Ahmadi Hari Wardoyo, Ryan F. Donnelly
Abstract
< 0.05) reduction of TNF-α production, a pro-inflammatory cytokine typically associated with the early onset of acute gout. Accordingly, CLC-loaded MAPs could represent a new minimally-invasive alternative strategy for management of acute gout.
Topics & Concepts
GoutColchicineChemistryMedicineBiochemistryInternal medicineProtein purification and stabilityAnimal Virus Infections StudiesToxin Mechanisms and Immunotoxins