Annulation of 2‐Alkynylanilines: The Versatile Chemical Compounds
Vaezeh Fathi Vavsari, Ali M. Nikbakht, Saeed Balalaie
Abstract
Abstract 2‐Alkynylanilines as versatile building blocks have been widely applied for the construction of nitrogen atom‐containing heterocycles in organic synthesis. The focus of this review is on the application of 2‐alkynylaniline and its derivatives in the metal‐catalyzed or metal‐free synthesis of various heterocycles including indoles, oxindoles, indazoles, benzisoxazoles, quinolines, benzoxazines, benzothiazines, quinazolines, cinnolines, and seven‐ and eight‐membered heterocycles.
Topics & Concepts
ChemistryAnnulationNitrogen atomCombinatorial chemistryNitrogenOrganic chemistryCatalysisGroup (periodic table)Catalytic C–H Functionalization MethodsSynthesis of Indole DerivativesSulfur-Based Synthesis Techniques