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TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2

Yuxuan Liu, Shan Wan, Xiaoqin Yang, Yi Wang, Wen-Juan Gan, Wen-Long Ye, Xiao‐Shun He, Junjie Chen, Yun Yang, Xuemei Yang, Xin Guo, Xiao‐Jiao Gao, Yitan Lu, Zhiyong Deng, Guang Hu, Hua Wu

2023Cell chemical biology34 citationsDOIOpen Access PDF

Topics & Concepts

DruggabilityUbiquitinCancer researchColorectal cancerMetastasisKinaseHippo signaling pathwayChemistryIn vivoBiologyCell biologyCancerGeneticsBiochemistryGeneHippo pathway signaling and YAP/TAZUbiquitin and proteasome pathwaysHereditary Neurological Disorders
TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2 | Litcius