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Leonurine attenuates cisplatin nephrotoxicity by suppressing the NLRP3 inflammasome, mitochondrial dysfunction, and endoplasmic reticulum stress

Qi Zhang, Qiuhong Sun, Yan Tong, Xiao Bi, Lin Chen, Jianxin Lü, Wei Ding

2022International Urology and Nephrology22 citationsDOI

Topics & Concepts

InflammasomePyrin domainMedicinePharmacologyCisplatinNephrotoxicityApoptosisAcute kidney injuryWestern blotEndoplasmic reticulumKidneyInternal medicineChemistryBiochemistryInflammationChemotherapyGeneChemotherapy-induced organ toxicity mitigationInflammasome and immune disordersAcute Kidney Injury Research
Leonurine attenuates cisplatin nephrotoxicity by suppressing the NLRP3 inflammasome, mitochondrial dysfunction, and endoplasmic reticulum stress | Litcius