Resemblance and differences in dietary restriction nephroprotective mechanisms in young and old rats
Nadezda V. Andrianova, Ljubava D. Zorova, Irina B. Pevzner, Vasily A. Popkov, Valery P. Chernikov, Д. Н. Силачев, Egor Y. Plotnikov, Dmitry B. Zorov
Abstract
levels, as well as lowered severity of the oxidative stress. Thus, the age-associated decline of protective signaling demands extended DR to achieve nephroprotective potential in old animals.
Topics & Concepts
Oxidative stressAutophagyLipid peroxidationMitochondrionInternal medicineEndocrinologyMedicineBiologyBiochemistryApoptosisDietary Effects on HealthGenetics, Aging, and Longevity in Model OrganismsHydrogen's biological and therapeutic effects