Litcius/Paper detail

Plasmid-Encoded Traits Vary across Environments

Sarai S. Finks, Jennifer B. H. Martiny

2023mBio40 citationsDOIOpen Access PDF

Abstract

Plasmids are well known for their role in the transmission of antibiotic resistance-conferring genes. Beyond human and clinical settings, however, they disseminate many other types of genes, including those that contribute to microbially driven ecosystem processes. In this study, we identified the distribution of traits genetically encoded by plasmids isolated from seven broadly categorized environments. We find that plasmid trait content varied with both bacterial host taxonomy and environment and that, on average, half of the plasmids were potentially mobilizable. As anthropogenic activities impact ecosystems and the climate, investigating and identifying the mechanisms of how microbial communities can adapt will be imperative for predicting the impacts on ecosystem functioning.

Topics & Concepts

PlasmidGeneBiologyAntibiotic resistanceGeneticsComputational biologyTransmission (telecommunications)BacteriaComputer scienceTelecommunicationsAntibiotic Resistance in BacteriaPharmaceutical and Antibiotic Environmental ImpactsBacteriophages and microbial interactions