Long-term arsenite exposure decreases autophagy by increased release of Nrf2 in transformed human keratinocytes
Jing Wu, Yiping Ni, Qianlei Yang, Jiayuan Mao, Xuerui Zhu, Shasha Tao, Koichi Kato, Jie Zhang, Dapeng Wang, Kenzo Yamanaka, Yan An
Topics & Concepts
AutophagyHaCaTDownregulation and upregulationPI3K/AKT/mTOR pathwayArseniteCell biologyProtein kinase BChemistryCancer researchBiologySignal transductionCell cultureBiochemistryApoptosisArsenicGeneticsGeneOrganic chemistryGenomics, phytochemicals, and oxidative stressArsenic contamination and mitigationAutophagy in Disease and Therapy