Litcius/Paper detail

Structural optimization and finite element analysis of poly‐<scp>l</scp>‐lactide acid coronary stent with improved radial strength and acute recoil rate

Kaikai Song, Yuying Bi, Haibin Zhao, Tim Wu, Feng Xu, Guoqun Zhao

2020Journal of Biomedical Materials Research Part B Applied Biomaterials34 citationsDOI

Abstract

Abstract Current poly‐ l ‐lactide acid (PLLA) scaffolds have issues of inadequate mechanical strength leading to thrombosis formation. Designing a novel bioabsorbable PLLA stent with a novel structure and improved mechanical property is urgently needed. In this study, stent structure modification and optimization based on bioresorbable vascular scaffold Version 1.1 (BVS 1.1, Abbott Laboratories) were conducted. The mechanical property of the redesigned stent was studied using both computerized finite element analysis and experimental mechanical deformation testing, including radial strength (RS), acute recoil (AR), foreshortening (FS), and bending stiffness (BS). The simulated and experimental results showed that the mechanical properties of the modified structure were significantly improved (modified stent vs. BVS 1.1: RS: 2.25 vs. 1.29 N/mm; AR: 3.03 vs. 4.41%; FS: 1.13 vs. 6.89%; BS: 1.49 vs. 0.72 N mm 2 ).

Topics & Concepts

Finite element methodRecoilMaterials scienceStentChemistryStructural engineeringPhysicsInternal medicineEngineeringMedicineAtomic physicsCoronary Interventions and DiagnosticsCardiac Imaging and DiagnosticsCerebrovascular and Carotid Artery Diseases