Balancing the Effect of Leukotrienes in Asthma
Catherine Godson
Abstract
A mouse model of airway contraction in asthma, together with analyses of the human lung, indicates that maresin conjugates, a family of lipid mediators, play a role in the resolution of inflammation. Might these lipids represent a pharmacologic target in the treatment of inflammatory disorders?
Topics & Concepts
AsthmaLipid signalingInflammationBronchoconstrictionMediatorImmunologyChemistryMedicineInternal medicineFatty Acid Research and HealthBiochemical Analysis and Sensing TechniquesImmune Response and Inflammation