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An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy

Benjamin R. Schrank, Yifan Wang, Annette Wu, Nhat Tran, DaeYong Lee, Jared Edwards, Kristin Huntoon, Shiyan Dong, JongHoon Ha, Yifan Ma, Adam Grippin, Seong Dong Jeong, Abin Antony, Mengyu Chang, Minjeong Kang, Thomas D. Gallup, Albert C. Koong, Jing Li, Kyuson Yun, Betty Y. S. Kim, Wen Jiang

2025Nature Cancer17 citationsDOIOpen Access PDF

Topics & Concepts

Listeriolysin OToxinCancer immunotherapyConjugateImmunotherapyAntibodyImmunotoxinMicrobiologyMedicineImmunologyBiologyImmune systemBacteriaMonoclonal antibodyListeria monocytogenesGeneticsListeriaMathematical analysisMathematicsBacteriophages and microbial interactionsCancer Research and TreatmentsMicrobial Inactivation Methods
An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy | Litcius