Oxidization enhances type I ROS generation of AIE-active zwitterionic photosensitizers for photodynamic killing of drug-resistant bacteria
Jianye Gong, Lingxiu Liu, Chunbin Li, Yumao He, Jia Yu, Ying Zhang, Lina Feng, Guoyu Jiang, Jianguo Wang, Ben Zhong Tang
Abstract
. This work elucidates the mechanism of the oxidization strategy for enhancing the ROS production ability of PSs and offers a new guideline for the exploitation of AIE-active type I PSs.
Topics & Concepts
Reactive oxygen speciesChemistryIntersystem crossingPhotosensitizerStackingPhotodynamic therapyCombinatorial chemistryCationic polymerizationIntermolecular forcePhotochemistryNanotechnologyMoleculeMaterials scienceOrganic chemistryBiochemistrySinglet stateNuclear physicsPhysicsExcited stateNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPhotodynamic Therapy Research Studies