Paeoniflorin ameliorates glycemic variability-induced oxidative stress and platelet activation in HUVECs and DM rats
Ye Huang, Jingshang Wang, Lin Yang, Long Yue, Lei Zhang, Yanhong Zhang, Yewen Song, Dandan Li, Zhixu Yang
Abstract
Glycemic variability (GV) plays an important role in the pathogenesis of vascular complications associated with diabetes mellitus (DM).
Topics & Concepts
PaeoniflorinOxidative stressDiabetes mellitusMedicineHuman umbilical vein endothelial cellReactive oxygen speciesPathogenesisGlycemicPharmacologyPlatelet activationEndothelial dysfunctionUmbilical veinInternal medicineEndocrinologyPlateletChemistryBiochemistryIn vitroChromatographyHigh-performance liquid chromatographyTraditional Chinese Medicine AnalysisAtherosclerosis and Cardiovascular DiseasesDiabetic Foot Ulcer Assessment and Management