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2D-MoS<sub>2</sub>-supported copper peroxide nanodots with enhanced nanozyme activity: application in antibacterial activity

A. Leela Siva Kumari, Jagabandhu Sahoo, Mrinmoy De

2023Nanoscale33 citationsDOI

Abstract

@CP) to achieve pH-dependent light-induced nanozyme-based antibacterial action. It has shown superior peroxidase and antibacterial activity at low pH. The mechanism behind the enhanced POD-like activity and high antibacterial activity was established. The mechanistic pathway involves estimating ROS generation, membrane depolarization, inner membrane permeabilization, metal ion release, and the effect of NIR on photothermal and photodynamic activities. Overall, our work highlighted the combinatorial approach for eradicating bacterial infections using enzyme-based antibacterial agents.

Topics & Concepts

Antibacterial activityPeroxidaseCopperPeroxideBroad spectrumNanodotPoint of deliveryNanotechnologyChemistryCombinatorial chemistryMaterials scienceBacteriaEnzymeBiochemistryOrganic chemistryBiologyGeneticsAgronomyAdvanced Nanomaterials in CatalysisAdvanced biosensing and bioanalysis techniquesNanocluster Synthesis and Applications
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