Stability matters, too – the thermodynamics of amyloid fibril formation
Alexander K. Buell
Abstract
the thermodynamic driving force) and how stable they actually are. In this review, I attempt to give an overview of the types of experiments that have been performed to-date to answer these questions, and to summarise our current understanding of amyloid thermodynamics.
Topics & Concepts
ThermodynamicsAmyloid fibrilAmyloid (mycology)ChemistryAmyloid βPhysicsMedicineInorganic chemistryPathologyDiseaseAlzheimer's disease research and treatmentsProtein Structure and DynamicsLipid Membrane Structure and Behavior