Activation of the tumor suppressive Hippo pathway by triptonide as a new strategy to potently inhibit aggressive melanoma cell metastasis
Shijie Tan, Zhe Zhao, Yingnan Qiao, Bin Zhang, Tong Zhang, Mengli Zhang, Jindan Qi, Xiaohua Wang, Mei Meng, Quansheng Zhou
Topics & Concepts
MelanomaCancer researchMicrophthalmia-associated transcription factorMetastasisHippo signaling pathwayBiologyTumor progressionCancerMedicineTranscription factorSignal transductionInternal medicineCell biologyBiochemistryGeneHippo pathway signaling and YAP/TAZCell death mechanisms and regulationWnt/β-catenin signaling in development and cancer