Redefining inflammatory macrophage phenotypes across stages and tissues by single-cell transcriptomics
P’ng Loke, Jian-Da Lin
Abstract
Single-cell transcriptomic data identifies major activation paths of monocyte-derived macrophages as a framework for inflammatory tissue macrophages.
Topics & Concepts
TranscriptomePhenotypeMacrophageCell biologyInflammationBiologyMonocyteCellInflammatory cellImmunologyGene expressionGeneGeneticsIn vitroImmune cells in cancerNeuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics