Litcius/Paper detail

Synthesis, biological evaluation and molecular docking studies of new pyrimidine derivatives as potent dual EGFR/HDAC inhibitors

G. Sivaiah, M.S. Raghu, S. Prasad, A.M. Anusuya, K. Yogesh Kumar, Fahd Alharethy, M.K. Prashanth, Byong‐Hun Jeon

2024Journal of Molecular Structure17 citationsDOI

Topics & Concepts

ChemistryDocking (animal)EGFR inhibitorsVorinostatPharmacophorePyrimidineEpidermal growth factor receptorHistone deacetylaseErlotinibHDAC1HDAC6A549 cellBiochemistryIC50PharmacologyIn vitroCombinatorial chemistryHistoneReceptorMedicineNursingGeneHistone Deacetylase Inhibitors ResearchBiochemical and Molecular ResearchQuinazolinone synthesis and applications
Synthesis, biological evaluation and molecular docking studies of new pyrimidine derivatives as potent dual EGFR/HDAC inhibitors | Litcius