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Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from Dubai

Susanna K. P. Lau, Kenneth S. M. Li, Hayes K. H. Luk, Zirong He, Jade L. L. Teng, Kwok‐Yung Yuen, U. Wernery, Patrick C. Y. Woo

2020mSphere23 citationsDOIOpen Access PDF

Abstract

Since its first appearance in 2012, Middle East respiratory syndrome (MERS) has affected >25 countries, with >2,400 cases and an extremely high fatality rate of >30%. The total number of mortalities due to MERS is already greater than that due to severe acute respiratory syndrome. MERS coronavirus (MERS-CoV) has been confirmed to be the etiological agent. So far, dromedaries are the only known animal reservoir for MERS-CoV. Previously published serological studies showed that sera of Bactrian camels were all negative for MERS-CoV antibodies. In this study, we observed that 41% of the Bactrian camel sera and 55% of the hybrid camel sera from Dubai (where dromedaries are also present), but none of the sera from Bactrian camels in Xinjiang (where dromedaries are absent), were positive for MERS-CoV antibodies. Based on these results, we conclude that in addition to dromedaries, Bactrian and hybrid camels are also potential sources of MERS-CoV infection.

Topics & Concepts

Middle East respiratory syndrome coronavirusBiologyAntibodyCase fatality rateSerologyMiddle East respiratory syndromeVeterinary medicineRespiratory systemCoronavirusVirologyEtiologyImmunologyCoronavirus disease 2019 (COVID-19)Internal medicineMedicineAnatomyEpidemiologyInfectious disease (medical specialty)DiseaseSARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesAnimal Diversity and Health Studies