Multifunctional protein-based self-assembled nanoplatform: overcoming hypoxic tumor microenvironment for enhanced imaging-guided photodynamic therapy
Min Li, Ziyi Cheng, Heng Liu, Kun Dou, Huan Xiao, Linlu Zhao, Fabiao Yu
Abstract
studies corroborate the remarkable anti-tumour efficacy of CIB NPs under NIR illumination, providing a significant advancement in PDT. The favourable biosafety profile of CIB NPs further emphasizes their potential for clinical application in hypoxic tumour therapy.
Topics & Concepts
Photodynamic therapyTumor microenvironmentChemistryIn situBODIPYHypoxia (environmental)Cancer researchBiophysicsNanotechnologyTumor cellsOxygenMedicineMaterials scienceFluorescenceBiologyQuantum mechanicsPhysicsOrganic chemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesCancer, Hypoxia, and Metabolism