DNA-PKcs promotes cardiac ischemia reperfusion injury through mitigating BI-1-governed mitochondrial homeostasis
Hao Zhou, Sam Toan, Pingjun Zhu, Jin Wang, Jun Ren, Yingmei Zhang
Topics & Concepts
CardioprotectionDNA damageCell biologyDNA-PKcsMitochondrial DNAReperfusion injuryApoptosisMitochondrionBiologyChemistryKinaseMolecular biologyIschemiaProtein kinase AMedicineDNAInternal medicineBiochemistryGeneMitochondrial Function and PathologyAutophagy in Disease and TherapyCardiac Ischemia and Reperfusion